2466. What’s Lurking in the Drain? Serial transmission of NDM-1Klebsiella pneumoniae to patients admitted 9 months apart to the same ICU room

ABSTRACT: Abstract

Background

We evaluated the role of an in-room sink in NDM-1 K. pneumoniae (NDMKP) transmission.

Methods

In October 2017, Infection Prevention (IP) initiated weekly point prevalence rectal screening cultures in 4 ICUs. In 3/2018, IP launched an epidemiologic and environmental investigation following identification of a patient with NDMKP rectal colonization. Environmental samples including swabs of biofilm from drains and water from p-traps were obtained from the in-room sink. Illumina whole-genome sequencing (WGS) was performed on all NDMKP patient and environmental isolates. Single nucleotide variants (SNVs) were identified against the reference Klebsiella pneumoniae strain MLST15 (NZ_CP022127), and isolates within 150 SNVs of each other were considered to be g

SUBMITTER: Smith B 

PROVIDER: S-EPMC6809693 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature