Detection of chlamydia infection within human testicular biopsies.

ABSTRACT:

Study question

Can Chlamydia be found in the testes of infertile men?

Summary answer

Chlamydia can be found in 16.7% of fresh testicular biopsies and 45.3% of fixed testicular biopsies taken from a selection of infertile men.

What is known already

Male chlamydial infection has been understudied despite male and female infections occurring at similar rates. This is particularly true of asymptomatic infections, which occur in 50% of cases. Chlamydial infection has also been associated with increased sperm DNA damage and reduced male fertility.

Study design, size, duration

We collected diagnostic (fixed, n = 100) and therapeutic (fresh, n = 18) human testicular biopsies during sperm recovery procedures from moderately to severely infertile men in a cross-sectional

SUBMITTER: Bryan ER 

PROVIDER: S-EPMC6810529 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature