Low-Dose Aspirin Use and Cognitive Function in Older Age: A Systematic Review and Meta-analysis.

ABSTRACT:

Objectives

To investigate whether low-dose aspirin (<300 mg/d) can influence the onset of cognitive impairment or dementia in observational studies and improve cognitive test scores in randomized controlled trials (RCTs) in participants without dementia.

Design

Systematic review and meta-analysis.

Setting

Observational and interventional studies.

Participants

Individuals with no dementia or cognitive impairment initially.

Measurements

Odds ratios (ORs) and 95% confidence intervals (CIs), adjusted for the maximum number of covariates from each study, were used to summarize data on the incidence of dementia and cognitive impairment in observational studies. Standardized mean differences (SMDs) were used for cognitive test scores in RCTs.

Results

Of

SUBMITTER: Veronese N 

PROVIDER: S-EPMC6810633 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature