Combining DC and AC electric fields with deterministic lateral displacement for micro- and nano-particle separation.

ABSTRACT: This paper describes the behavior of particles in a deterministic lateral displacement (DLD) separation device with DC and AC electric fields applied orthogonal to the fluid flow. As proof of principle, we demonstrate tunable microparticle and nanoparticle separation and fractionation depending on both particle size and zeta potential. DLD is a microfluidic technique that performs size-based binary separation of particles in a continuous flow. Here, we explore how the application of both DC and AC electric fields (separate or together) can be used to improve separation in a DLD device. We show that particles significantly smaller than the critical diameter of the device can be efficiently separated by applying orthogonal electric fields. Following the application of a DC voltage, Faradaic

SUBMITTER: Calero V 

PROVIDER: S-EPMC6811356 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature