Neuronal Stem Cell and Drug Interactions: A Systematic Review and Meta-Analysis: Concise Review.

ABSTRACT: Stem cell therapy is a promising treatment option for neurodegenerative diseases that mostly affect geriatric patients who often suffer from comorbidities requiring multiple medications. However, not much is known about the interactions between stem cells and drugs. Here, we focus on the potential interactions between drugs used to treat the comorbidities or sequelae of neurodegenerative diseases and neuronal stem cells to reveal potential effects on drug safety and efficacy. To determine the potential effects of drugs frequently used in geriatric patients (analgesic, antibiotic, antidepressant, antidiabetic, antihyperlipidemic, and antihypertensive drugs) on neuronal stem cell differentiation and proliferation, we systematically searched PubMed to identify nonreview articles published in

SUBMITTER: Ikhsan M 

PROVIDER: S-EPMC6811698 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature