Human Milk Fatty Acid Composition Is Associated with Dietary, Genetic, Sociodemographic and Environmental Factors in the CHILD Cohort (P08-114-19)

ABSTRACT: Abstract

Objectives

Human milk fatty acids impact infant growth and development, and their composition is highly variable. We aimed to characterize milk fatty acid composition in a large pregnancy cohort and identify factors that influence their variability.

Methods

Among 1094 mothers from the CHILD cohort, we analyzed milk collected at 3–4 months postpartum. Fatty acids were measured by high-resolution capillary gas-liquid chromatography. Individual fatty acids, total saturated (SFA), monounsaturated (MUFA), n3 and n6-polyunsaturated fatty acids (n3-PUFA and n6-PUFA) were analyzed as standard deviation scores and using principal components analysis (PCA). Maternal diet, sociodemographic, health and environmental factors were self-reported. Single-nucleotide polymorphisms

SUBMITTER: Miliku K 

PROVIDER: S-EPMC6811717 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature