Prevalence of chronic kidney disease in the elderly using the ASPirin in Reducing Events in the Elderly study cohort.

ABSTRACT:

Aim

The prevalence of chronic kidney disease (CKD) in the elderly is controversial because age-related decline in kidney function may not truly reflect underlying kidney disease. We estimate the baseline prevalence and predictors of CKD using the CKD Epidemiology Collaboration (CKD-EPI_eGFR ) and Berlin Initiative Study 1 (BIS1_eGFR ) eGFR equations in the ASPirin in Reducing Events in the Elderly (ASPREE) trial cohort of healthy older participants.

Methods

GFR was estimated using CKD-EPI and BIS1 equations. CKD was defined as eGFR <60 mL/min/1.73 m² or ≥ 60 mL/min/1.73 m² with urine albumin creatinine ratio (UACR) ≥ 3 mg/mmol. Logistic regression was used to identify predictors of CKD prevalence defined by each eGFR equation.

Res

SUBMITTER: Polkinghorne KR 

PROVIDER: S-EPMC6812602 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature