Weight change across adulthood in relation to all cause and cause specific mortality: prospective cohort study.

ABSTRACT:

Objective

To investigate the association between weight changes across adulthood and mortality.

Design

Prospective cohort study.

Setting

US National Health and Nutrition Examination Survey (NHANES) 1988-94 and 1999-2014.

Participants

36 051 people aged 40 years or over with measured body weight and height at baseline and recalled weight at young adulthood (25 years old) and middle adulthood (10 years before baseline).

Main outcome measures

All cause and cause specific mortality from baseline until 31 December 2015.

Results

During a mean follow-up of 12.3 years, 10 500 deaths occurred. Compared with participants who remained at normal weight, those moving from the non-obese to obese category between young and middle adulthood had a 22% (hazard rati

SUBMITTER: Chen C 

PROVIDER: S-EPMC6812615 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature