Central sensitization predicts greater fatigue independently of musculoskeletal pain.

ABSTRACT: OBJECTIVES:To test whether central sensitization was associated with greater fatigue, independently of musculoskeletal pain. METHODS:2477 prospective cohort study participants completed a baseline questionnaire comprising the Chalder Fatigue Scale (CFQ), pain, demographics, physical activity, anxiety, depression and medication use. In a clinical assessment of 290 (11.7%) participants, central sensitization was measured by the wind-up ratio test at the hand (WUR-H) and foot (WUR-F). Bioelectric impedance determined proportion body fat. All participants were followed up 12 months later, at which time they completed the CFQ. Linear regression, with inverse probability sampling weights, tested the relationship between WUR at baseline and CFQ at 12 months, adjusted for baseline CFQ, demographic

SUBMITTER: Druce KL 

PROVIDER: S-EPMC6812719 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature