Prediction of protein architectures involved in the signaling-pathway initiating sporulation in Firmicutes.

ABSTRACT:

Objectives

Like many other proteins, those belonging to the signal transduction cascade initiating sporulation (Spo0 pathway) have conserved protein domains (Capra and Laub in Annu Rev Microbiol 66:325-47, 2012). Improvements in bioinformatics applications to discover proteins involved in the initiation of the sporulating cascade in newly sequenced genomes is an important task that requires rigorous comparative genomic methods and manual curation to identify endospore-forming bacteria. This note aims to present a collection of predicted proteins involved in the Spo0 pathway found in the proteomes of fully sequenced and manually curated endospore-forming Firmicutes species. This collection may serve as a guide to conduct future experiments in endospore formers in genomic and metagen

SUBMITTER: Martinez-Amador P 

PROVIDER: S-EPMC6813101 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature