An Updated Nomogram for Predicting Invasiveness in Preoperative Ductal Carcinoma In Situ of the Breast.

ABSTRACT:

Purpose

To validate and update a nomogram for predicting ductal carcinoma in situ (DCIS) upstaging in preoperative biopsy.

Materials and methods

Medical records of 444 preoperative DCIS patients were evaluated and used to validate a previous version of the Severance nomogram for predicting DCIS upstaging in preoperative biopsy. Patients were divided into two groups according to the final postoperative pathology. Univariate and multivariate analyses with the chi-square test, Student's t-test, and binary logistic regression method identified new significant variables. The updated nomogram was evaluated with the C-index and Hosmer-Lemeshow goodness of fit test.

Results

The area under a receiver operating characteristic curve for comparison with the previous nomogram was

SUBMITTER: Kim S 

PROVIDER: S-EPMC6813145 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature