Atypical Amygdala-Neocortex Interaction During Dynamic Facial Expression Processing in Autism Spectrum Disorder.

ABSTRACT: Atypical reciprocal social interactions involving emotional facial expressions are a core clinical feature of autism spectrum disorder (ASD). Previous functional magnetic resonance imaging (fMRI) studies have demonstrated that some social brain regions, including subcortical (e.g., amygdala) and neocortical regions (e.g., fusiform gyrus, FG) are less activated during the processing of facial expression stimuli in individuals with ASD. However, the functional networking patterns between the subcortical and cortical regions in processing emotional facial expressions remain unclear. We investigated this issue in ASD (n = 31) and typically developing (TD; n = 31) individuals using fMRI. Participants viewed dynamic facial expressions of anger and happiness and their corresponding mosaic images.

SUBMITTER: Sato W 

PROVIDER: S-EPMC6813184 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature