Estimated Impact of Screening on Gonorrhea Epidemiology in the United States: Insights From a Mathematical Model.

ABSTRACT: The burden of gonorrhea infections in the United States is high. There are marked disparities by race/ethnicity and sexual orientation. We quantified the impact of screening and treatment on gonorrhea rates in the US population aged 15 to 39 years for the period 2000 to 2015 and estimated the impact that alternative screening strategies might have had over the same period.

Methods

We developed a national-level transmission model that divides the population by race/ethnicity, preferred gender of sex partners, age, gender, and sexual activity level. We compared our fitted model ("base case") to 4 alternative strategies: (i) no screening, (ii) full adherence to current screening guidelines, (iii) annual universal screening, or (iv) enhanced screening in groups with the highest infectio

SUBMITTER: Tuite AR 

PROVIDER: S-EPMC6813831 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature