RNA-Seq based transcriptome analysis during bovine viral diarrhoea virus (BVDV) infection.

ABSTRACT: BACKGROUND:Bovine viral diarrhoea virus (BVDV) is the member of the genus Pestivirus within the Flaviviridae family and responsible for severe economic losses in the cattle industry. BVDV can employ 'infect-and-persist' strategy and 'hit-and-run' strategy to remain associated with hosts and thus contributes to BVDV circulation in cattle herds. BVDV have also evolved various strategies to evade the innate immunity of host. To further understand the mechanisms by which BVDV overcomes the host cell innate immune response and provide more clues for further understanding the BVDV-host interaction, in this descriptive study, we conducted a investigation of differentially expressed genes (DEGs) of the host during BVDV infection by RNA-Seq analysis. RESULTS:Our analysis identified 1297, 1732, 3072

SUBMITTER: Liu C 

PROVIDER: S-EPMC6813989 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature