An eight-mRNA signature predicts the prognosis of patients with bladder urothelial carcinoma.

ABSTRACT:

Background

Bladder cancer is one of the most common cancers, and its histopathological type is mainly bladder urothelial carcinoma, accounting for about 90%. The prognostic biomarkers of bladder cancer are classified into clinical features biomarkers and molecular biomarkers. Nevertheless, due to the existence of individual specificity, patients with similar pathological characteristics still have great differences in the risk of disease recurrence. Therefore, it is often inaccurate to predict the survival status of patients based on clinical characteristic biomarkers, and a prognostic molecular biomarker that can grade the risk of bladder cancer patients is needed.

Methods

A total of three bladder urothelial carcinoma datasets were used in this study from the Cancer Genome

SUBMITTER: Zhu R 

PROVIDER: S-EPMC6814068 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature