Metandem: An online software tool for mass spectrometry-based isobaric labeling metabolomics.

ABSTRACT: Mass spectrometry-based stable isotope labeling provides the advantages of multiplexing capability and accurate quantification but requires tailored bioinformatics tools for data analysis. Despite the rapid advancements in analytical methodology, it is often challenging to analyze stable isotope labeling-based metabolomics data, particularly for isobaric labeling using MS/MS reporter ions for quantification. We report Metandem, a novel online software tool for isobaric labeling-based metabolomics, freely available at http://metandem.com/web/. Metandem provides a comprehensive data analysis pipeline integrating feature extraction, metabolite quantification, metabolite identification, batch processing of multiple data files, online parameter optimization for custom datasets, data normalizati

SUBMITTER: Hao L 

PROVIDER: S-EPMC6814207 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature