Battery-free, lightweight, injectable microsystem for in vivo wireless pharmacology and optogenetics.

ABSTRACT: Pharmacology and optogenetics are widely used in neuroscience research to study the central and peripheral nervous systems. While both approaches allow for sophisticated studies of neural circuitry, continued advances are, in part, hampered by technology limitations associated with requirements for physical tethers that connect external equipment to rigid probes inserted into delicate regions of the brain. The results can lead to tissue damage and alterations in behavioral tasks and natural movements, with additional difficulties in use for studies that involve social interactions and/or motions in complex 3-dimensional environments. These disadvantages are particularly pronounced in research that demands combined optogenetic and pharmacological functions in a single experiment. Here, we p

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC6815115 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature