White matter hyperintensity burden in patients with ischemic stroke treated with thrombectomy.

ABSTRACT:

Introduction

To determine the influence of white matter hyperintensity (WMH) burden on functional outcome, rate of symptomatic intracerebral hemorrhage (sICH), and procedural success in patients with acute ischemic stroke (AIS) treated by mechanical thrombectomy (MT) with current stentriever/aspiration devices.

Methods

Patients with AIS due to large vessel occlusion (LVO) from the Thrombectomie des Artères Cérébrales (THRACE) trial and prospective cohorts from 2 academic comprehensive stroke centers treated with MT were pooled and retrospectively analyzed. WMH volumes were obtained by semiautomated planimetric segmentation and tested in association with the rate of favorable outcome (90-day functional independence), substantial recanalization after MT, and sICH.

Results</

SUBMITTER: Boulouis G 

PROVIDER: S-EPMC6815208 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature