Vascular Health of Children Conceived via In Vitro Fertilization.

ABSTRACT:

Objective

To evaluate whether in vitro fertilization (IVF) has an effect on the cardiovascular health of offspring.

Study design

This was a cross-sectional pilot study. We performed vascular health assessment for 17 children aged 10-14 years who were conceived via IVF with autologous oocytes at Stanford University. Carotid artery ultrasound evaluated intima-media thickness and stiffness, carotid-femoral pulse wave velocity determined segmental arterial stiffness, and endothelial pulse amplitude testing assessed endothelial function. We compared IVF offspring with control adolescents assessed in the same laboratory, with all comparisons adjusted for age, sex, and race/ethnicity.

Results

All participants had normal body mass index and blood pressure. Compared with contr

SUBMITTER: Zhang WY 

PROVIDER: S-EPMC6815705 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature