3D-T1ρ prepared zero echo time-based PETRA sequence for in vivo biexponential relaxation mapping of semisolid short-T2 tissues at 3 T.

ABSTRACT: BACKGROUND:In addition to the articular cartilage, osteoarthritis (OA) affects several other tissues such as tendons, ligaments, and subchondral bone. T1ρ relaxation study of these short T2 tissues may provide a more comprehensive evaluation of OA. PURPOSE:To develop a 3D spin-lattice relaxation in the rotating frame (T1ρ ) prepared zero echo time (ZTE)-based pointwise encoding time reduction with radial acquisition (3D-T1ρ -PETRA) sequence for relaxation mapping of semisolid short-T2 tissues on a clinical 3 T scanner. STUDY TYPE:Prospective. POPULATION:Phantom, two bovine whole knee joint and Achilles tendon specimens, 10 healthy volunteers with no known inflammation, trauma or pain in the knee or ankle. FIELD STRENGTH/SEQUENCE:A customized PETRA sequence to acquire fat-suppressed 3D T1ρ

SUBMITTER: Sharafi A 

PROVIDER: S-EPMC6816051 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature