CHIPOFIL: A pilot study assessing the feasibility of HIPEC without extracorporeal circuit.

ABSTRACT:

Background

Heated intraperitoneal chemotherapy (HIPEC) is currently performed using an external circuit including a heating device and a pump. Available devices have several drawbacks in terms of costs, technique (flow surges due to blocked tubes) and staff safety, hindering a wider use. In a previous preclinical study conducted in animals, we placed a heating wire within the abdomen to achieve and maintain hyperthermia. Our results showed this technique is safe and effective. The present pilot study was conceived as the first use of such a device in humans, aiming to confirm its safety and efficacy.

Methods

This was a pilot study designed to include 13 patients undergoing HIPEC. Two sets of the prototype were placed within the abdominal cavity, one in the supramesocolic and

SUBMITTER: Ortega-Deballon P 

PROVIDER: S-EPMC6816282 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature