Aspirin Compared with Anticoagulation to Prevent Venous Thromboembolism After Knee or Hip Arthroplasty: a Large Retrospective Cohort Study.

ABSTRACT:

Background

Although guidelines now allow the use of aspirin as an alternative to anticoagulants for venous thromboembolism prophylaxis after knee or hip arthroplasty, there is limited data on contemporary use and outcomes with aspirin.

Objective

To describe the use of pharmacologic thromboprophylaxis and to assess venous thromboembolic risk with aspirin compared with anticoagulation after knee or hip arthroplasty.

Design

Retrospective cohort study using data from the US MedAssets database.

Patients

Adults with a principal discharge diagnosis of knee or hip arthroplasty between January 1, 2013, and December 31, 2014.

Main measures

We identified charges for medications used for thromboprophylaxis within 7 days after the index surgery from billing records.

SUBMITTER: Baumgartner C 

PROVIDER: S-EPMC6816584 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature