Neural connectivity during affect labeling predicts treatment response to psychological therapies for social anxiety disorder.

ABSTRACT:

Background

Although psychological treatments for social anxiety disorder (SAD) can be highly effective, many individuals do not respond to treatment. Identifying factors associated with improved outcomes can facilitate individualized treatment choices. We investigated whether patterns of neural connectivity predicted treatment responses and whether treatment type, cognitive behavioral therapy (CBT) or acceptance and commitment therapy (ACT), moderated this effect.

Methods

Participants with SAD (n = 34) underwent fMRI prior to treatment and completed implicit and explicit emotion regulation tasks. Neural connectivity measures were estimates of amygdala-prefrontal cortex connectivity. Treatment responder status was defined using the 'clinically significant change index' (Loeri

SUBMITTER: Young KS 

PROVIDER: S-EPMC6816743 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature