The CDKN2A polymorphisms and the susceptibility of HBV-related gestational diabetes mellitus.

ABSTRACT:

Background

Single-nucleotide polymorphisms (SNPs) were discovered in HBV-related gestational diabetes mellitus, but it still unclear whether these SNPs are associated with the susceptibility of HBV-related gestational diabetes mellitus.

Methods

The investigation of the association between CDKN2A polymorphisms and occurrence of HBV-related gestational diabetes mellitus (GDM) in Chinese was assessed in the case-control study. A total of 480 pregnant patients with HBV and 530 pregnant controls were consecutively recruited from January 2015 to December 2016. Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP) method was applied to measure genotyping for the detection of CDKN2A.

Results

The significant differences in the frequency of CDKN2A genot

SUBMITTER: Wang S 

PROVIDER: S-EPMC6816994 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature