Evaluation of the Virclia^® automated chemiluminescent immunoassay system for diagnosing pneumonia caused by Mycoplasma pneumoniae.

ABSTRACT:

Background

Mycoplasma pneumoniae is considered an important etiologic agent of community-acquired pneumonia (CAP) in outpatients. We aimed to evaluate the diagnostic accuracy of a quick automated chemiluminescent immunoassay (CLIA) for M. pneumoniae in a population-based prospective study of CAP.

Methods

A total of 137 outpatients diagnosed with CAP were included in the study. Acute- and convalescent phase sera were analyzed for IgG and IgM to M. pneumoniae with both CLIA (VirClia^® ) and ELISA immunoassays. Conventional serological criteria by quantitative ELISA were considered as reference standard. Sensitivity and specificity of the assay were assessed with the construction of receiver operating characteristic (ROC) curves, and the kappa index was used to evalua

SUBMITTER: Ortiz de la Tabla V 

PROVIDER: S-EPMC6816995 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature