Hepatocellular Carcinoma Incidence Is Decreasing Among Younger Adults in the United States.

ABSTRACT:

Background & aims

Incidence rates for hepatocellular carcinoma (HCC) increased rapidly in the United States since the 1990s, but have plateaued or started to decrease in other industrialized countries. It unclear if and when a similar trend will be observed in the United States. We examined trends in HCC incidence rates in the United States by age, sex, and race/ethnicity of patients.

Methods

We calculated age-adjusted HCC incidence rates using data from the Surveillance, Epidemiology, and End Results program of cancer registries from 1992 through 2015. We estimated incidence rates by 10-year age group and used joinpoint regression to quantify the magnitude and direction of trends, overall and by sex and race/ethnicity (non-Hispanic white, non-Hispanic black, Hispanic, and A

SUBMITTER: Rich NE 

PROVIDER: S-EPMC6817412 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature