Metabolic Syndrome and Risk of Ischemic Stroke in Atrial Fibrillation: ARIC Study.

ABSTRACT: Background and Purpose- Metabolic syndrome (MetS), a prothrombotic state, is associated with an increased risk of atrial fibrillation (AF) and stroke. The CHA₂DS₂-VASc score does not account for the MetS components of prehypertension, prediabetes mellitus, abdominal obesity, elevated triglycerides, and low HDL (high-density lipoprotein). Data are limited on the association of MetS with stroke in AF, independent of CHA₂DS₂-VASc variables. Our aim was to identify MetS components associated with ischemic stroke in participants with AF in the ARIC study (Atherosclerosis Risk in Communities). Methods- We included 1172 participants with incident AF within 5 years of measurement of MetS components. MetS was defined by ATP criteria and International Diab

SUBMITTER: Decker JJ 

PROVIDER: S-EPMC6817422 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature