Is there evidence for efficacy of human papillomavirus vaccination in solid organ transplant recipients?

ABSTRACT: Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections worldwide and is associated with precancerous lesions and cancers of the cervix, vulva, vagina, penis, anus, tonsils and base of the tongue. Several studies show an increased risk of HPV-associated cancers in solid organ transplant recipients (SOTR). The aims of this review are to investigate the evidence of efficacy for the HPV vaccination in transplant recipients and to discuss the known national guidelines. A systematic literature search has been conducted to identify studies where SOTR received the HPV vaccination to evaluate the efficacy of the HPV vaccine on this population. The primary outcome was antibody response against the HPV genotypes included in the vaccines and the secondary outcom

SUBMITTER: Vinkenes E 

PROVIDER: S-EPMC6817653 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature