Effectiveness of radiotherapy after breast-conserving surgery in older patients with T1-2N0 breast cancer.

ABSTRACT:

Purpose

In the Netherlands, radiotherapy after breast-conserving surgery (BCS) is omitted in up to 30% of patients aged ≥ 75 years. Although omission of radiotherapy is considered an option for older women treated with endocrine treatment, the majority of these patients do not receive systemic treatment following Dutch treatment guidelines. Therefore, the aim of this study was to evaluate the effect of omission of radiotherapy on locoregional recurrence risk in this patient population.

Methods

Patients aged ≥ 75 years undergone BCS for T1-2N0 breast cancer diagnosed between 2003 and 2009 were selected from the Netherlands Cancer Registry. To minimize confounding by indication, hospital variation was used to assess the impact of radiotherapy-use on locoregional recurrence ris

SUBMITTER: de Boer AZ 

PROVIDER: S-EPMC6817758 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature