CD62P and P10 as predictive markers for assessing the efficacy of hemodialysis in treating end-stage renal disease.

ABSTRACT:

Background

CD62P is a platelet α-granule membrane protein, and P10 is a platelet membrane glycoprotein thrombospondin. To better understand the effects of hemodialysis (HD), we have conducted this study to investigate CD62P and P10 in assessing the efficacy of HD in treating patients with end-stage renal disease (ESRD).

Methods

The case group consisted of 111 patients suffering ESRD treated with regular HD and the control group enrolled 117 healthy subjects. Before and after HD treatment, a series of parameters were observed, based on which, CD62P and P10 levels were detected in the patients in two groups before and after HD therapy. The correlation analysis analyzed the correlations of CD62P and P10 markers with serum creatinine (Scr), blood urea nitrogen (BUN), and subject

SUBMITTER: Yu JR 

PROVIDER: S-EPMC6818603 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature