Quality of Life of Patients With Osteosarcoma in the European American Osteosarcoma Study-1 (EURAMOS-1): Development and Implementation of a Questionnaire Substudy.

ABSTRACT:

Background

The quality of life (QoL) of patients with osteosarcoma (OS) may be adversely affected by the disease or its treatment. Therefore, it is important to understand the QoL of patients undergoing treatment for OS to improve the QoL. We report on the first prospective international QoL study that was embedded within a large randomized clinical trial from 4 national study groups.

Objective

This paper aimed to describe the QoL study development, methodology, accrual details, and characteristics of the QoL cohort.

Methods

A total of 2260 patients registered in the EURopean AMerican Osteosarcoma Study-1 (EURAMOS-1), of whom 97.92% (2213/2260) were eligible for the optional QoL assessment and could participate in terms of questionnaire availability. Overall, 61.86% (

SUBMITTER: Calaminus G 

PROVIDER: S-EPMC6819132 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature