Negative life experiences contribute to racial differences in the neural response to threat.

ABSTRACT: Threat-related emotional function is supported by a neural circuit that includes the prefrontal cortex (PFC), hippocampus, and amygdala. The function of this neural circuit is altered by negative life experiences, which can potentially affect threat-related emotional processes. Notably, Black-American individuals disproportionately endure negative life experiences compared to White-American individuals. However, the relationships among negative life experiences, race, and the neural substrates that support threat-related emotional function remains unclear. Therefore, the current study investigated whether the brain function that supports threat-related emotional processes varies with racial differences in negative life experiences. In the present study, adolescent violence exposure, family

SUBMITTER: Harnett NG 

PROVIDER: S-EPMC6819267 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature