Psychological and social consequences of non-invasive prenatal testing (NIPT): a scoping review.

ABSTRACT:

Background

Genomics-based noninvasive prenatal tests (NIPT) allow screening for chromosomal anomalies such as Down syndrome (trisomy 21). The technique uses cell-free fetal DNA (cffDNA) that circulates in the maternal blood and is detectable from 5 weeks of gestation onwards. Parents who choose to undergo this relatively new test (introduced in 2011) might be aware of its positive features (i.e. clinical safety and ease of use); however, they might be less aware of the required decisions and accompanying internal conflicts following a potential positive test result. To show the evidence on psychological and social consequences of the use of NIPT, we conducted a scoping review.

Methods

We systematically searched four electronic databases (MEDLINE (Ovid), Cochrane Library (Wil

SUBMITTER: Labonte V 

PROVIDER: S-EPMC6819451 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature