Changes in brain activity after weight loss.

ABSTRACT:

Objectives

The importance of the regulatory role of the brain in directing glucose homeostasis, energy homeostasis, eating behaviour, weight control and obesity is increasingly recognized. Brain activity in (sub)cortical neuronal networks involved in homeostatic control and hedonic responses is generally increased in persons with obesity. Currently, it is not known if these functional changes can be affected by dieting. The aim of the current study was to investigate whether prolonged fasting and/or weight loss influences neuronal brain activity in obese persons.

Methods

Fourteen participants with obesity were included (two male participants and 12 female participants, body mass index 35.2 ± 1.2 kg m^-2). Whole-brain resting-state functional magnetic resonance imag

SUBMITTER: van Opstal AM 

PROVIDER: S-EPMC6819976 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature