Negative epidemiological association between HSV-1 and HSV-2 infections.

ABSTRACT:

Objectives

Existing evidence on an epidemiological association between herpes simplex virus (HSV) type 1 and type 2 infections remains conflicting and inconclusive. Using a multi-national database of HSV-1/2 serological testing, we aimed to assess the existence of an association between both infections.

Design setting and participants

An HSV-1/2 cross-sectional serological testing database was assembled by merging databases of seroprevalence studies on men blood donors residing currently in Qatar, but from different countries. Specimens were tested for anti-HSV-1 IgG antibodies using HerpeSelect® 1 ELISA, and for anti-HSV-2 IgG antibodies following a two-test algorithm: HerpeSelect® 2 ELISA to test the sera, and Euroline-WB to confirm positive and equivocal specimens. Logist

SUBMITTER: Nasrallah GK 

PROVIDER: S-EPMC6820085 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature