Streptococcus mutans isolated from a 4-year-old girl diagnosed with infective endocarditis.

ABSTRACT: Objectives:Infective endocarditis (IE) has an extremely high fatality rate. In this study, we isolated a strain of Streptococcus mutans, which we called HM, from the blood drawn from a 4-year-old girl diagnosed with IE. We aimed to fully type the HM strain and investigate its biological properties, including its virulence with respect to IE. Material and methods:A 16S rRNA phylogenetic tree and glucosyltransferase gene sequences were used to type HM. Serotyping was performed using the Ouchterlony method. Morphological observations were made using phase contrast and electron microscopy. Fibrinogen adhesion and biofilm formation were investigated to examine the tissue colonization properties of HM, whereas its bodily origin was determined from its fingerprinting pattern. Results:The isolated

SUBMITTER: Kondo Y 

PROVIDER: S-EPMC6820803 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature