Estimating plasma glucose with the FreeStyle Libre Pro continuous glucose monitor during oral glucose tolerance tests in youth without diabetes.

ABSTRACT: Few studies have assessed the accuracy of the FreeStyle Libre Pro (FLP) continuous glucose monitor for estimating plasma glucose (PG) in non-diabetic children.

Objective

Determine the accuracy of FLP compared to PG during OGTT in healthy children.

Subjects

Children (7-11.99 years) with healthy weight and overweight/obesity (n = 33; 52% male).

Methods

Participants wore the FLP before and during a 2-hour OGTT; PG was measured at 30 minutes intervals. Potential systematic- and magnitude-related biases for FLP vs PG were examined.

Results

FLP 15-minute averages and PG were correlated at most timepoints during OGTT (r² = 0.35-0.69, P's < .001 for time point 30-120 minutes) and for PG area under the curve (AUC) (r² = 0.65, P < .0001). There were

SUBMITTER: Ghane N 

PROVIDER: S-EPMC6821586 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature