Shared Neural Phenotypes for Mood and Anxiety Disorders: A Meta-analysis of 226 Task-Related Functional Imaging Studies.

ABSTRACT:

Importance

Major depressive disorder, bipolar disorder, posttraumatic stress disorder, and anxiety disorders are highly comorbid and have shared clinical features. It is not yet known whether their clinical overlap is reflected at the neurobiological level.

Objective

To detect transdiagnostic convergence in abnormalities in task-related brain activation.

Data source

Task-related functional magnetic resonance imaging articles published in PubMed, Web of Science, and Google Scholar during the last decade comparing control individuals with patients with mood, posttraumatic stress, and anxiety disorders were examined.

Study selection

Following Preferred Reporting Items for Systematic Reviews and Meta-analyses reporting guidelines, articles were selected if they rep

SUBMITTER: Janiri D 

PROVIDER: S-EPMC6822098 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature