Immunomodulatory activities of Acacia catechu, a traditional thirst quencher of South India.

ABSTRACT: BACKGROUND:Acacia catechu has been widely used in Ayurveda for treating many diseases. Its heartwood extract is used in asthma, cough, bronchitis, colic, diarrhea, dysentery, boils, skin afflictions, sores and for stomatitis. The decoction of heartwood is used for drinking purpose in southern part of India especially in Kerala. OBJECTIVE:The current study was carried out to evaluate immunomodulatory effects of heartwood extracts of A. catechu in Swiss albino mice. MATERIAL AND METHODS:In vivo immunomodulatory activity was analyzed by hemagglutinating antibody (HA) titer, plaque forming cell assay and delayed type hypersensitivity (DTH). In vitro immunomodulatory potential of the extracts was studied using peritoneal macrophages and splenocytes from mice. Effect of extracts on phagocytic ac

SUBMITTER: Sunil MA 

PROVIDER: S-EPMC6822161 | biostudies-literature | 2019 Jul - Sep

REPOSITORIES: biostudies-literature