Trypanosoma cruzi infection associated with atypical clinical manifestation during the acute phase of the Chagas disease.

ABSTRACT:

Background

Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi and is transmitted by triatomine insects. Clinical manifestations vary according to the phase of the disease. Cutaneous manifestations are usually observed in the acute phase (chagoma and Romaña's sign) or after reactivation of the chronic phase by immunosuppression; however, a disseminated infection in the acute phase without immunosuppression has not been reported for CD. Here, we report an unusual case of disseminated cutaneous infection during the acute phase of CD in a Mexican woman.

Methods

Evaluation of the patient included a complete clinical history, a physical exam, and an exhaustive evaluation by laboratory tests, including ELISA, Western blot and PCR.

Results

Skin biopsies

SUBMITTER: Rangel-Gamboa L 

PROVIDER: S-EPMC6822409 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature