Caenorhabditis elegans as a tool for environmental risk assessment: emerging and promising applications for a "nobelized worm".

ABSTRACT: Caenorhabditis elegans has been an invaluable model organism in research fields such as developmental biology and neurobiology. Neurotoxicity is one of the subfields greatly profiting from the C. elegans model within biomedical context, while the corresponding potential of the organism applied to environmental studies is relevant but has been largely underexplored. Within the biomedical scope, the implication of metals and organic chemicals with pesticide activity (hereinafter designated as pesticides) in the etiology of several neurodegenerative diseases has been extensively investigated using this nematode as a primary model organism. Additionally, as a well-known experimental model bearing high sensitivity to different contaminants and representing important functional lev

SUBMITTER: Queiros L 

PROVIDER: S-EPMC6823147 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature