Inflammation Mediates Body Weight and Ageing Effects on Psychomotor Slowing.

ABSTRACT: Inflammation (immune system activation) affects neuronal function and may have consequences for the efficiency and speed of functional brain processes. Indeed, unusually slow psychomotor speed, a measure predictive of behavioural performance and health outcomes, is found with obesity and ageing, two conditions also associated with chronic inflammation. Yet whether inflammation is the mediating factor remains unclear. Here, we assessed inflammation by indexing interleukin-6 level in blood and measured psychomotor speed as well as indices of selective visual attention in young (mean = 26 years) or old (mean = 71 years) adults (N = 83) who were either lean or currently significantly overweight (mean body mass index = 22.4 and 33.8, respectively). Inflammation was positively and significantly

SUBMITTER: Balter LJT 

PROVIDER: S-EPMC6823347 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature