STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse.

ABSTRACT: Multi-omics approaches use a diversity of high-throughput technologies to profile the different molecular layers of living cells. Ideally, the integration of this information should result in comprehensive systems models of cellular physiology and regulation. However, most multi-omics projects still include a limited number of molecular assays and there have been very few multi-omic studies that evaluate dynamic processes such as cellular growth, development and adaptation. Hence, we lack formal analysis methods and comprehensive multi-omics datasets that can be leveraged to develop true multi-layered models for dynamic cellular systems. Here we present the STATegra multi-omics dataset that combines measurements from up to 10 different omics technologies applied to the same biological syst

SUBMITTER: Gomez-Cabrero D 

PROVIDER: S-EPMC6823427 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature