Deciphering Ancestral Sex Chromosome Turnovers Based on Analysis of Male Mutation Bias.

ABSTRACT: The age of sex chromosomes is commonly obtained by comparing the substitution rates of XY gametologs. Coupled with phylogenetic reconstructions, one can refine the origin of a sex chromosome system relative to specific speciation events. However, these approaches are insufficient to determine the presence and duration of ancestral sex chromosome systems that were lost in some species. In this study, we worked with genomic and transcriptomic data from mammals and squamates and analyzed the effect of male mutation bias on X-linked sequences in these groups. We searched for signatures indicating whether monotremes shared the same sex chromosomes with placental mammals or whether pleurodonts and acrodonts had a common ancestral sex chromosome system. Our analyses indicate that platypus did not

SUBMITTER: Acosta A 

PROVIDER: S-EPMC6823514 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature