Proteomic studies of putative molecular signatures for biological effects by Korean Red Ginseng.

ABSTRACT:

Background

Korean Red Ginseng (KRG) has been widely used as an herbal medicine to normalize and strengthen body functions. Although many researchers have focused on the biological effects of KRG, more studies on the action mechanism of red ginseng are still needed. Previously, we investigated the proteomic changes of the rat spleen while searching for molecular signatures and the action mechanism of KRG. The proteomic analysis revealed that differentially expressed proteins (DEPs) were involved in the increased immune response and phagocytosis. The aim of this study was to evaluate the biological activities of KRG, especially the immune-enhancing response of KRG.

Methods

Rats were divided into 4 groups: 0 (control group), 500, 1000, and 2000 mg/kg administration of KRG powde

SUBMITTER: Lee YY 

PROVIDER: S-EPMC6823813 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature