Epidemiologic Trends in Clostridioides difficile Infections in a Regional Community Hospital Network.

ABSTRACT:

Importance

Clostridioides difficile infection (CDI) remains a leading cause of health care facility-associated infection. A greater understanding of the regional epidemiologic profile of CDI could inform targeted prevention strategies.

Objectives

To assess trends in incidence of health care facility-associated and community-acquired CDI among hospitalized patients over time and to conduct a subanalysis of trends in the NAP1 strain of CDI over time.

Design, setting, and participants

This long-term multicenter cohort study reviewed records of patients (N = 2 025 678) admitted to a network of 43 regional community hospitals primarily in the southeastern United States from January 1, 2013, through December 31, 2017. Generalized linear mixed-effects models were used to adj

SUBMITTER: Turner NA 

PROVIDER: S-EPMC6824221 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature