Characterizing the Health-Related Quality of Life Burden of Overactive Bladder Using Disease-Specific Patient-Reported Outcome Measures: A Systematic Literature Review.

ABSTRACT: INTRODUCTION:The objective was to identify the most commonly used patient-reported outcome (PRO) instruments for overactive bladder (OAB), determine which are the most useful for measuring burden in OAB and characterize the findings of recent studies that have employed PRO instruments to assess OAB symptoms and the effects of treatment. METHODS:A systematic search of OAB literature published between January 2006 and November 2017 using Medline/PubMed and EMBASE databases. RESULTS:Of 3425 abstracts and 500 full-text articles reviewed, 58 studies (both clinical trials and observational studies) were included in the review. The most commonly used PRO instruments were the OAB Questionnaire (OAB-q; 64%), followed by the King's Health Questionnaire (KHQ; 31%) and the Patient Perception of Bladde

SUBMITTER: Johnston KM 

PROVIDER: S-EPMC6824512 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature