Atypical Clinical Manifestations of Loiasis and Their Relevance for Endemic Populations.

ABSTRACT:

Background

Loiasis is mostly considered a relatively benign infection when compared with other filarial and parasitic diseases, with Calabar swellings and eyeworm being the most common signs. Yet, there are numerous reports in the literature of more serious sequelae. Establishing the relationship between infection and disease is a crucial first step toward estimating the burden of loiasis.

Methods

We conducted a systematic review of case reports containing 329 individuals and detailing clinical manifestations of loiasis with a focus on nonclassical, atypical presentations.

Results

Results indicate a high proportion (47%) of atypical presentations in the case reports identified, encompassing a wide range of cardiac, respiratory, gastrointestinal, renal, neurological, o

SUBMITTER: Buell KG 

PROVIDER: S-EPMC6824532 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature