Alkyne Hydroheteroarylation: Enantioselective Coupling of Indoles and Alkynes via Rh-Hydride Catalysis.

ABSTRACT: We report an enantioselective coupling between alkynes and indoles. A Rh-hydride catalyst isomerizes alkynes to generate a metal-allyl species that can be trapped with both aromatic and heteroaromatic nucleophiles.

SUBMITTER: Cruz FA 

PROVIDER: S-EPMC6824589 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature