Effect of anticoagulation therapy in older patients with chronic kidney disease and atrial fibrillation: A meta-analysis.

ABSTRACT:

Background

The role of anticoagulation therapy for stroke prevention in older atrial fibrillation (AF) patients with chronic kidney disease (CKD) remains unclear. Therefore, we conducted a meta-analysis to explore the efficacy and safety of anticoagulation therapy in this population.

Methods

The Cochrane Library, PubMed, and Embase databases were systematically searched for studies reporting the effect of anticoagulation therapy in older patients with AF and CKD. The risk ratios (RRs) and 95% confidence intervals (CIs) were regarded as the risk estimates. A random-effects model selected was to evaluate the treatment outcomes. The presentations were based on the Preferred Reporting Items for reporting systematic reviews and meta-analyses statement.

Results

A total of 7

SUBMITTER: He W 

PROVIDER: S-EPMC6824694 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature